What is an Epstein-Barr nuclear antigen EBNA?

What is an Epstein-Barr nuclear antigen EBNA?

EBV nuclear antigen (EBNA) Antibody to EBNA, determined by the standard immunofluorescent test, is not seen in the acute phase of EBV infection but slowly appears two to four months after onset of symptoms and persists for the rest of a person’s life. Other EBNA enzyme immunoassays may report false positive results.

What is EBV VCA IgA positive?

A positive serum IgA VCA titer indicates previous repeated infection by the virus or frequent reactivation of latent EBV in B cells. This has been used as a screening tool to identify subjects at high risk of NPC,4,5 as well as being a diagnostic criteria for undifferentiated NPC.

How is VCA IgG used to classify EBV?

The presence of VCA IgG in the absence of VCA IgM and EBNA-1 IgG antibodies makes classifying EBV infection more difficult as this serological picture can be seen in the case of past infection with EBNA-1 IgG loss or non-appearance, or acute infections with the early disappearance or delayed onset of VCA IgM.

When do you get an EBV EA test?

Interpretation Provides information to assist in interpretation of the test results. The presence of antibody to the early antigen (EA) of Epstein-Barr virus (EBV) indicates that EBV is actively replicating. Generally, this antibody can only be detected during active EBV infection, such as in patients with infectious mononucleosis.

What are the lab codes for EBV antibodies?

not present Lab Order Codes: E EBVS S Synonyms: A Anti-EBV Antibodies; EBV Serology; CPT Codes: 8 86664 – EBV antibody, EBNA (Ig 8 86665 x2 – EBV antibody, VCA Test Includes: A Anti-EBV Antibodies – Viral Caps

How many outpatients had EBV in 2005?

The aim of this study was to assess the prevalence of this pattern in 2,422 outpatients with suspected EBV infection examined in 2005-2006, and to interpret its significance by means of immunoblotting.