What is tuber Cinereum hamartoma?

What is tuber Cinereum hamartoma?

Tuber cinereum hamartoma is a benign tumor in which a disorganized collection of neurons and glia accumulate at the tuber cinereum of the hypothalamus on the floor of the third ventricle. It is a congenital malformation, included on the spectrum of gray matter heterotopias.

How is hypothalamic hamartoma diagnosed?

Hypothalamic hamartomas are diagnosed by assessment of neurological symptoms, magnetic resonance imaging (MRI), and neurological tests. Early detection can improve the likelihood of successful treatment, especially for children who have worsening seizures or whose learning skills or behavior have begun to deteriorate.

What is the function of tuber Cinereum?

Function. The tuber cinereum primarily constitutes nerve fibres travelling from the hypothalamus to the pituitary gland. Rather than providing signalling to the gland, many of these fibres actually function as the source of the substances released by the posterior lobe of this gland.

Can you have a laughing seizure?

People having a gelastic seizure (GS) sound like they are laughing or mumbling. This is an uncontrolled reaction caused by unusual electrical activity in the part of the brain that controls these actions. Gelastic seizures are named after the greek word for laughter, “gelastikos.”

What cell is known to project to tuber Cinereum mainly?

Size ranges from 5 to 50 mm in diameter, but is usually between 10 and 30 mm in diameter. They primarily consist of neurons and glial cells.

Should hamartoma be removed?

Surgical excision is the definitive treatment. Hamartomas have the same malignant potential as normal breast tissue, unless greater than 6 cm, and thus do not require any additional treatment than one would for adenoma or other benign lesions.

What is hypothalamic rage?

Hypothalamic hamartomas (HH) are rare, tumor-like malformations that occur during fetal development and are present at birth. They are non-progressive lesions and do not expand, spread or metastasize to other locations.

Is a hamartoma a tumor?

A hamartoma (from Greek hamartia, meaning “fault, defect,” and -oma, denoting a tumor or neoplasm) is a benign (noncancerous) tumorlike malformation made up of an abnormal mixture of cells and tissues found in areas of the body where growth occurs.

What is the main function of the Infundibulum?

The infundibulum catches and channels the released eggs; it is the wide distal (outermost) portion of each fallopian tube. The endings of the fimbriae extend over the ovary; they contract close to the ovary’s surface during ovulation in order to guide the free egg.

How to tell if you have a tuber cinereum hamartoma?

Any nodularity within should raise the suspicion of a tuber cinereum (hypothalamic) hamartoma. Small, non-enhancing mass lesion contiguous with the tuber cinereum is almost always diagnostic of tuber cinereum hamartoma.

Where does a hypothalamic hamartoma occur in the brain?

Dr Rohit Sharma and Dr Donna D’Souza ◉ et al. Hypothalamic hamartomas, also known as tuber cinereum hamartomas, are benign non-neoplastic heterotopias in the brain that typically occur in the region of the hypothalamus, arising from the tuber cinereum, a part of the hypothalamus located between the mammillary bodies and the optic chiasm. Article:

How to diagnose hypothalamic hamartoma on a CT scan?

On conventional axial CT images, the diagnosis can be challenging, depending on slice position and thickness, although with more recent volumetric scans with coronal and sagittal reformats, the abnormality is easier to identify.

Is the hamartoma a malignant or focal malformation?

A hamartoma is a focal malformation that resembles (but is not) a neoplasm (cf. other CNS neoplasms); it is not a malignant tumor, and it is composed of tissue elements normally found at that site that grow in a disorganized mass.